Botanical care often promises deep roots while selling thin proof, and that gap is where O Positiv has tried to work. Brianna Bitton came with years of painful cycles and undiagnosed PCOS, Bobby Bitton came with startup experience, and from a shared apartment they built FLO, then URO and MENO, around named extracts and outside lab checks.
The start was a rented apartment in Los Angeles, where Brianna Bitton lived with her brother Bobby Bitton and they spoke about unmet needs.
Brianna had spent time as a celebrity interior designer and as a former Disney Imagineer, and she recalls long years of sore periods that took her time. Bobby had trained in entrepreneurship and held jobs in young companies. In 2018 Brianna brought him the concept for FLO, a PMS gummy vitamin, and after long periods of tasting, testing and speaking with physicians and researchers, they brought it straight to buyers as the opening O Positiv product.
The line today is wider. FLO stays the entry, and the range has expanded toward URO for vaginal health and MENO for menopause, with the firm counting above 1.3 million customers and 24 products by 2023, plus an expected Target debut that December. The stated aim is to stand with women from first period to long past last.
What often goes unseen is the record keeping behind that expansion. Each manufacturing batch is checked by an outside lab for purity and potency, recipes are called OB/GYN formulated, and the URO probiotics list a studied strain with no artificial flavors or dyes. For Root to Bottle, that is the path to trace, from materia medica and harvest to bottle and label.
You were raised by a father who led his own interior design studio and a mother who held patents as an inventor, and you have said they taught you that ideas can be made real. How did growing up in that home shape the way the two of you collaborate today?
Brianna: Our parents kept repeating that an idea of mine could be made into something real. Dad operated his independent interior design business, and Mom invented and held several patents, so building was ordinary at home. I am a former Disney Imagineer and lived through years of hard periods before I felt that enough was enough. While based in LA as a celebrity interior designer, I noticed PMS ate my hours and the market offered nothing proactive for my signs.
Bobby: I had trained in entrepreneurship and understood commerce fairly well. A strong concept matters, yet we realized we had to plan how to produce and sell those inventions. Even now, our clear and separate duties stay central to our progress. When one of us arrives with ego, the other quickly calls it out.
Brianna: Much of starting a company rests on follow through. There were certainly hurdles on the road, yet those hurdles make the result meaningful. Our proudest result is clearly easing daily life for women.
In 2018 you were roommates discussing PMS and menopause at the kitchen table, while your mother moved through menopause and you lived with undiagnosed PCOS. What did those talks reveal that nothing on the store shelf seemed to provide?
Brianna: Living under one roof, we noticed two absences together. Mom was passing through menopause with limited help, and I was coping with severe PMS and PCOS that had no name yet. Choices seemed backward looking. You waited for signs to show, then you coped as well as possible. I hoped for a daily plant centered option I could use ahead of time, tied to research on its parts.
Bobby: Brianna pitched FLO to me in 2018. She carried direct experience and product sense. I carried young company practice. We devoted years to sampling, lab work and talks with physicians and researchers before we settled the recipe for FLO, the first gummy vitamin made for PMS. That method became our model. We refused to sell on assertion alone. We sought reviewed evidence for the parts and a form people would truly use each day.
URO lists a clinically studied probiotic strain and notes it is OBGYN formulated. For a shopper reading the label, what is truly inside the capsule and what does clinically studied signify in this case?
Brianna: URO grew from our response to vaginal health needs after FLO. The Vaginal Probiotic plus Multivitamin Capsule joins a probiotic with a daily multivitamin foundation. The URO Vaginal Probiotic Gummy is our pink pineapple chew with a studied strain, shaped with OB/GYNs, free from artificial flavors or dyes. By studied strain we point to the exact strain code kept on record, not the wider species.
Bobby: Living microbes demand tighter origin records. We buy from a supplier that banks strains and can record strain identity, live count to expiry, and holding needs. Every inbound batch comes with its own certificate of analysis, and completed goods are checked by an outside laboratory. The Medical Advisory Board, which brings OB/GYNs and an integrative womens health ND, studies recipe and wording. We print what the panel carries and what component research reports, and we keep therapy claims off the label.
Each production run is said to be third party tested for purity and potency. Take us through that process, from arriving ingredient to final lot release.
Bobby: Work begins before dispatch. We clear vendors against standards for identity, strength and allowed heavy metals and microbes. Inbound components carry a vendor certificate of analysis linked to a batch code. Our contract maker reviews those papers, draws samples from the batch, and verifies fit with the standard before manufacture starts.
Brianna: Through encapsulation or gummy pouring, staff log manufacturing records. Those logs list batch codes consumed, machines, heat levels, weights and staged controls. After the run finishes, reserve samples go to a separate lab to confirm purity and potency. Sale release goes only to batches that satisfy the standard. A batch that misses the standard never leaves.
Bobby: Shoppers meet a brief form of that trail on the Supplement Facts box and the other ingredients list, with marks or claims where relevant. The long form sits in our batch archive. That archive lets us reply to where precisely did this originate, and what proves it. Through a batch code and a lab sheet.
We sought peer reviewed backing for the ingredients and a format people would truly use daily.
Brianna Bitton and Bobby Bitton
By 2023 you shared more than 1.3 million customers, 24 products and funding of 3.2 million dollars, plus a Target launch set for that December. How did that growth alter sourcing and quality control?
Bobby: Growth made us stricter, not looser. FLO alone involved a narrow list of components. URO plus MENO, across capsules, gummies and washes, multiplied vendors and standards. We unified standards, fixed approved growers and fermentation allies where workable, and retained checks on each manufacturing batch instead of shifting to occasional batch checks.
Brianna: Store placement laid on further needs. A Target debut calls for barcodes, shipping cases, shelf life proof and retailer compliance files, all joined to the same batch framework. Our vow did not shift, research supported blends that bring felt positive results, supported by a 30 day risk free guarantee. That vow stands only when the jar in a shop in December equals the jar screened in a lab in August. So we put funds toward files and toward clear duties. Even now, our clear and separate duties stay central to our progress.

FLO arrived as a gummy instead of a capsule or tablet. From a formulation angle, what did that format demand for sourcing, flavor and fill?
Brianna: A gummy must deserve counter space. When flavor turns chalky or medicinal, use drops before a cycle ends. We ran many cycles to settle texture plus taste while skipping artificial flavors or dyes, a rule we carried into URO. The matrix differs from a capsule. You handle gelling media, acids that give tang, and aromas that last through storage.
Bobby: On supply, each input needs clearance by batch. Plant extracts ship with an extract ratio and a vendor certificate of analysis, and we match identity and strength to requirement. Gummies also demand tight handling of water activity and piece weight spread, so every unit holds its planned fill. The route took more time than tablets, yet steady use was the goal. A daily type only helps when taken daily.

Your site called O Positiv an OBGYN recommended brand based on IQVIA ProVoice surveys of 300 OBGYNs. What should a thoughtful reader take that survey to show, and what does it fail to show?
Bobby: We present it as a poll sign, and we label it that way. In US IQVIA ProVoice polls of n equals 300 OB/GYNs, O Positiv appears as an OB-GYN recommended brand. That says something about stated recommendation inside that group. It never stands in for batch records or component trials, and it says nothing about personal results. We hold those classes apart.
Brianna: The Medical Advisory Board keeps our wording exact. We shape recipes with OB/GYN guidance, we employ a studied strain wherever the pack claims one, and we screen each manufacturing batch. The poll is a single point a shopper may balance with the Supplement Facts box, the other ingredients list, and the testing claim. We wish the shelf to read clearly. Who shaped it, which strain or extract sits within, who checked it, and which batch it traces toward.
There are stages you can trace grower by grower and stages that stay blended through brokers or flavor houses. Where is O Positiv clearest today, and what would allow fuller openness?
Brianna: Our clearest ground is completed goods checks and recipe inputs. We can point to strain codes, extract standards, checks on each manufacturing batch, and board review. Those facts are filed batch by batch. Public sightlines fade farther up, beyond our immediate vendors, around single fields or fermentation vessels that rotate with season.
Bobby: Complete field mapping would demand farm kept batches held apart through extraction with no mixing, with open posting of certificates per batch. That fits certain herbs and fits poorly for aromas, gummy matrices and mixed source vitamins. Progress needs vendor terms that keep farm identity intact through drying and extraction, plus a pack or QR link that joins a finished batch to those sheets. We advance there where supply permits, and we state openly where a link stays blended instead of single source.
Closing note from the desk
What remains from this talk is shared sibling work. Brianna brought bodily need plus faith in a daily form that earns repeat use, Bobby brought standards, lab proof and growth, and both held wording within what papers allow.
O Positiv chose to center womens health as a lead subject rather than a side note, from first period to long past last, with forward looking daily types and independent checks by batch. Field mapping stays partial, and the founders state that limit instead of hiding it.
Product spotlight
Vaginal Probiotic plus Multivitamin Capsule, 36.99 dollars. A daily capsule uniting a vaginal probiotic and a multivitamin foundation. The pack lists a studied strain and OB/GYN shaping. Use daily per pack guidance and scan Supplement Facts plus other ingredients for complete makeup.
Vaginal Probiotic Gummy, 28.99 dollars. A pink pineapple daily chew for vaginal health, crafted with a studied strain and without artificial flavors or dyes. Chew form aids steady daily use. Use daily per guidance and review batch and Supplement Facts information on pack.







